Overview of Aflatoxin B1 Contamination in Traditional Chinese Medicine

Abstract

Abstract: Objective To summarize aflatoxins B1 contamination in traditional Chinese medicines (TCMs). Methods References from 2000 to now at home and abroad about the positive Results of AFB1 in TCMs were collated, summarized and analyzed. Results AFB1 were detected in 1 168 batches of 149 TCMs (including 11 animal medicines and 3 fermented medicines). Compared with the other medical parts, fruits and seeds, roots and rhizomes were more easily contaminated with AFB1. The rate of exceed standard (limit standard, 5 μg·kg-1) in the positive samples reached 52.40%, and the detection values of AFB1 among the TCMs were different significantly. Conclusion Contamination of AFB1 in TCMs is common. In the future, research on detection menthod, limit standard and anti-mild maintenance of AFB1 in TCMs should be strengthened.

Key words: traditional Chinese medicine, aflatoxin B1, toxicity, limited standard, contamination

CLC Number:

R917

ZHAO Xiangsheng, YING Guangyao, WEI Jianhe, SUN Hua, YANG Meihua. Overview of Aflatoxin B1 Contamination in Traditional Chinese Medicine[J]. Chinese Journal of Pharmacovigilance, 2018, 15(10): 608-616.

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