Chinese Journal of Pharmacovigilance ›› 2018, Vol. 15 ›› Issue (2): 78-82.

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Utilization of Ribavirin Injection Among Reproductive Population Aged 18 to 44 Years Old Based on Yinzhou District Healthcare Database

LI Hai-long1, ZHAO Hou-yu1, LIN Hong-bo3, LIU Cui-li2, SHEN Peng3, ZHAN Si-yan1,*   

  1. 1 Department of Epidemiology and Bio-statistics, School of Public Health, Peking University, Beijing 100191, China;
    2 Center for Drug Revaluation, CFDA, Beijing 100045, China;
    3 Yinzhou District Center for Disease Control and Prevention, Zhejiang Ningbo 315100, China
  • Received:2017-12-20 Revised:2018-03-28 Online:2018-02-20 Published:2018-03-28

Abstract: Objective To describe the clinical utilization of ribavirin injection among reproductive population in Yinzhou district, Ningbo city. Methods A descriptive analysis of the clinical utilization of ribavirin injection among reproductive population aged 18 to 44 in 3 general hospitals and 24 community health centers from 2010 to 2016 was conducted by using Yinzhou healthcare information database. Results During the study period, it was found that there were 363 882 outpatients' prescriptions of ribavirin injection and 206 511 ribavirin users. According to the instructions, the number of ribavirin injections prescription which met the requirement of each dose and daily dose accounted for 85.59% and 90.33% of the total number of ribavirin injection prescriptions respectively. Among our study population, there were 617 patients who had a diagnosis of pregnancy within 6 months of ribavirin prescription. Conclusion The results indicated that there were large amount of irrational prescriptions of ribavirin. Clinicians should adhere to the indication of ribavirin injection and requirement of dose, and be cautious when prescript to reproductive patients.

Key words: ribavirin, pregnancy, drug utilization, rational drug use

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