Chinese Journal of Pharmacovigilance ›› 2010, Vol. 7 ›› Issue (10): 577-578.

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The Impact of Xu Duan Tong Luo Pian on Nerve Conduction Velocity of Experimental Diabetic Rats

YANG Xiao-hui ,DENG Yuan-yuan   

  1. Dongfang Hospital Affiliated to Beijing University of Chinese Medicine, Beijing 100078, China
  • Received:2010-08-06 Revised:2016-03-12 Online:2010-10-08 Published:2016-03-09

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Abstract: Objective To observe the impact of Xu Duan Tong Luo Pian(XDTLP) on nerve conduction velocity(NCV) of experimental diabetic peripheral neuropathy(DPN) rats. Methods Diabetic rats were induced by STZ celiac injection. Then, the rats which successfully became diabetic model were divided into diabetic model group. Methycobal was given by 0.25mg/kg·d, XDTLP was given by3.2、6.3、12.6g/kg·d herb according to low, middle and high dose, which lasted 8 weeks. Results After treatment with XDTLP for8 weeks, NCV increased greatly. Conclusion The experiment showed that XDTLP can significantly improve the nerve conductive velocity in rats with DPN.

Key words: Xu Duan Tong Luo Pian, diabetic peripheral neuropathy, experimental research

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