Abstract: Objective Analysis of adverse drug reaction and their treatment costs for clinical therapy to reduce the medical expenses the cost of providinga scientific basis. Methods Retrospective analysis of 140 cases of adverse drug reaction caused by the direct costs and indirect costs were analyzed. Results 140 cases of adverse drug reaction cases. Mainly for anti-infective drugs(50.71%), followed by cardiovascular drugs(12.14%), ADR mainly the skin and appendages, was followed by the digestive system, nervous system. The average treatment time per patient is 2.69 days per patient due to adverse drug reaction due to the direct cost to 112.11 yuan, an indirect cost of 100.10 yuan. Conclusion Based on the analysis of treatment costs of adverse drug reaction, ADR occurred to patients and society of the heavy financial burden, should be greater monitoring of economic costs of ADR, and to take measures to mitigate the social costs and patients ADR.

Key words: adverse drug reaction(ADR), cost, analysis