Chinese Journal of Pharmacovigilance ›› 2010, Vol. 7 ›› Issue (9): 554-555.

Previous Articles     Next Articles

Adverse Drug Reaction Induced by Antidepressants of SSRI and SNRI

ZHANG Ying1 ,CUI Xiang-li2* ,YANG Ping2, JIA Ying2, LIU Jing2, PAN Hua3 ,ZHAO Zhi-gang2   

  1. 1.Pharmaceutical Equipment and Material Management, Tiantan Hospital, Capital Medical University, Beijing 100050 China;
    2.Department of Pharmacy, Tiantan Hospital, Capital Medical University, Beijing 100050 China;
    3.Neurology Department, Tiantan Hospital, Capital Medical University, Beijing 100050, China
  • Received:2010-06-23 Revised:2016-03-09 Online:2010-09-08 Published:2016-03-09

PDF (PC)

636

Abstract: Objective To study the clinical syndrom of adverse drug reaction(ADR) induced by SSRI or SNRI, and the treatment of ADR. Methods 24 depression cases with ADR induced by SSRI or SNRI were collected in neurological outpatients from January,2010 to June,2010, we analysised the clinical syndroms of ADR induced by SSRI or SNRI, and de-scribed the treatment of different ADR. Results The most common ADR is Gastrointestinal tract reaction, less comman ADR are Psychiatric symptoms, autonomic nervous system dysfunction and extrapyramidal reaction. Conclusion Although SSRI and SNRI are most safe antidepressants, neurologists should pay much attention to their ADR, and grasp the treatment measures.

Key words: selective serotonin reuptake inhibitors(SSRI), serotonin/norepinephrine reuptake inhibitors(SNRI), adverse drug reaction(ADR), treatment measures

CLC Number: