Chinese Journal of Pharmacovigilance ›› 2026, Vol. 23 ›› Issue (7): 817-819.
DOI: 10.19803/j.1672-8629.20250652

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One case of airway spasm caused by rocuronium bromide injection

Qian Xia, Guo Zhigang*, Zheng Liguang   

  1. Department of Pharmacy, Peking University School and Hospital of Stomatology, National Center of Stomatology, National Clinical Research Center for Oral Diseases, National Engineering of Research Center of Oral Biomaterials and Digital Medical Devices, Beijing 100081, China
  • Received:2025-09-12 Online:2026-07-15 Published:2026-07-16

Abstract: Objective To investigate the characteristics of such adverse reactions as airway spasm induced by rocuronium bromide injection, and to provide a reference for safe medication. Methods One case of intraoperative airway spasm caused by rocuronium injection in an 8-year-old patient was analyzed. Based on literature, the related adverse reactions and possible mechanisms were studied while treatment regimens were recommended. Results After discontinuation of the drug and symptomatic treatment, the patient gradually improved. By reviewing drug instructions and literature, it was found that the correlations between rocuronium bromide injection and airway spasm were “possible”. Conclusion During clinical anesthesia, the risk of airway spasm caused by rocuronium bromide injection deserves attention to ensure the safety of patients.

Key words: Rocuronium Bromide Injection, Airway Spasm, Muscle Relaxant Drug, Adverse Drug Reaction

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