Abstract: Objective To observe the clinical efficacy and safety of etomidate combined with propofol in painless abortion anesthesia. Method 80 patients with painless induced abortion admitted from March, 2015 to March, 2016 were randomly divided into two groups. The patients in the control group were treated with propofol + sufentanil anesthesia. The patients in the experimental group were treated with etomidate + propofol and sufentanil. The correlation of clinical indexes, anesthesia related indexes, surgical events and adverse reactions were compared between the two groups. Result There were no significant differences in SpO₂, MAP and HR between the two groups (P> 0.05). The recovery time and recovery time of the patients in the experimental group were significantly lower than those in the control group (P <0.01). The incidence of injection pain and overall adverse reaction in the experimental group was significantly lower than that in the control group (P <0.05). Conclusion The combination of etomidate and propofol has obvious clinical effect in painless induced abortion. It has the characteristics of quicker recovery and fewer adverse reactions.

Key words: painless abortion, etomidate, propofol, anesthesia