Chinese Journal of Pharmacovigilance ›› 2017, Vol. 14 ›› Issue (2): 87-89.

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Rapid Identification of Different Processed Products of Rehmannia Glutinosa Formula Granules by FTIR

ZHOU Ming-xia1, GAO Hui-qin1, PENG Xiong-ying1, LI Ya-tao1, LI Jun-shan1, 2*, QU Yun-ping ,LI Zhen-jiang1   

  1. 1 Shineway Pharmaceutical Group Ltd., Hebei Shijiazhuang 051430, China;
    2 TCM Formula Granule Engineering Technology Research Center of Hebei, Hebei Shijiazhuang, 050200, China
  • Received:2017-03-10 Revised:2017-03-10 Online:2017-02-20 Published:2017-03-10

Abstract: Objective To establish a rapid FTIR method for identifying different processed products of Rehmannia glutinosa formula granules.Methods Various processed products were researched by infrared, second derivative spectra and two-dimensional correlation spectroscopy.Results In second derivative spectra, it existed differences among the intensity, shape and position of the peaks in the range of 1 200 ~ 1 800 cm-1, and the two-dimensional correlation spectroscopy were different obviously.Conclusion By comparing the infrared spectra, second derivative spectra and two-dimensional correlation spectroscopy, the different processed products of Rehmannia glutinosa formula granules could be identified rapidly and accurately.

Key words: Fourier transform infrared spectroscopy, second derivative spectrum, 2D-RIRcorrelation spectra, Rehmannia glutinosa, formula granules

CLC Number: