Analysis of 372 Cases of Adverse Drug Reactions Induced by Ornidazole Sodium Chloride Injection

Abstract

Abstract: Objective To investigate the features of adverse drug reaction(ADR) induced by ornidazole sodium chloride injection, so as to provide advice for reducing adverse reaction rate and to promote the safe drug use in clinic. Methods The ADR cases induced by ornidazole sodium chloride injection were searched between January 2014 and December 2016 in our hospital. Patients' basic characteristics, medication situation，clinical manifestation, clinical feature, ADR time and drug use were statistically analyzed. Results The female cases were more than the males. Patients' age was from 21 to 80 years old. The ADRs mostly occurred in the process of medication. Main manifestations were digestive reactions, nervous reaction, et al. There were 11 serious ADR cases, 261 cases had the combination of drug use. Conclusion The patients treated with ornidazole sodium chloride injection should be closely monitored. The infusion should be scientifically arranged the sequence when multi-drugs are used, so as to avoid potential risks.

Key words: ornidazole sodium chloride injection, adverse drug reaction(ADR), rational use of drugs

CLC Number:

R994.11

ZHANG Li-jun,SONG Jiao-jiao. Analysis of 372 Cases of Adverse Drug Reactions Induced by Ornidazole Sodium Chloride Injection[J]. Chinese Journal of Pharmacovigilance, 2017, 14(10): 622-625.

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