Abstract: Objective To investigate the pharmacodynamic value of sufentanil inhibiting laryngeal mask insertion reaction in the induction of propofol anesthesia. Methods 80 patients undergoing general anesthesia were randomly divided into two groups: research group received propofol induced+sufentanil and control group received propofol induced +fentanyl, compared between two groups of patients at different points of bis, blood pressure and heart rate, adverse reactions and induction time. Results There was no significant difference in blood pressure and heart rate between the two groups at different time points (P >0.05). The incidence of overall adverse reaction in research group was significantly lower than that in control group, and there was significant difference (P <0.05). There was no significant difference in the induction time of anesthesia between the two groups (P >0.05). Conclusion The inhibitory effect of sufentanil on the intubation of laryngeal mask is high in the induction of propofol anesthesia.

Key words: propofol, sufentanil, laryngeal mask intubation reaction, induction of anesthesia