Study on the Preparation Process of Tazarotene Cream and Its Stability

Abstract

Abstract: Objective To study the preparation process of tazarotene cream and its stability. Methods Orthogonal design was used to optimize the formula of tazrotene cream. The determination of tazarotene was carried out by HPLC method. Results The optimal formulation contained carbomer 934P, carbomer 1342, liquid paraffin as consistency regulator, span-80 as asemulsifier, benzyl alcohol as preservatives, disodium edetate as sequestering agent. Conclusion The preparation process of tazarotene is simple and available, the quality and stability of the tazarotene cream is good.

Key words: tazarotene, cream, assay, stability, orthogonal experiment

CLC Number:

R944

DENG Jian-hua,YANG Hong,WANG Fu-dong. Study on the Preparation Process of Tazarotene Cream and Its Stability[J]. Chinese Journal of Pharmacovigilance, 2016, 13(3): 146-147.

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URL: https://zgywjj.magtechjournal.com/EN/

https://zgywjj.magtechjournal.com/EN/Y2016/V13/I3/146

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Study on the Preparation Process of Tazarotene Cream and Its Stability

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