Abstract: Objective To optimize the best preparation technology of Qianliean concentrated pill and control its resolving time in quality standard range. Methods In the condition of the fixed drying temperature and drying time, orthogonal test was performed with the dissolving time as index. Results The best preparation technology of Qianliean concentrated pill was A2B1C2, thus using the plan B, in which Curcumae Radix, Salviae Miltiorrhizae Radix et Rhizoma, Acori Tatarinowii Rhizoma, and Phellodendri Chinensis Cortex were made powder, and the others remained were extracted. The powder fineness was 80 mesh, and paste proportion was 1.30. Conclusion The comprehensive quality of Qianliean concentrated pill was greatly improved under the optimizated extraction technology by orthogonal test. In this case, the moisture content of pills was controlled in the range of 6~7.5%, and resolving time was in full compliance with the provision.

Key words: orthogonal test, Qianliean concentrated pill, preparation technology, dissolving time