Abstract: Objective To investigate the problems in outpatient and emergency prescriptions in order to improve prescription quality and promote rational use. Methods58 556 outpatient and emergency prescriptions of our hospital in 2010 were randomly selected. The irrational prescriptions were classified and analyzed in respect of writing and rationality of drug use according to Prescription Management, Guiding principles for clinical application of antibiotics, New Edited Pharmacy, Chinese Clinical Drug Use Principle and Hospital Prescription Evaluation and Management(trial) issued in 2010. ResultsThere were 2 506 irrational prescriptions, accounting for 4.28%. Among the total, nonstandard prescriptions, inaptitude medication prescriptions, abnormal prescriptions were respectively accounted for 9.34%、81.76%、8.90%. ConclusionAfter a series of measures were carried out, the unqualified rate of the second half year gradually decreased with the first half year. The quality of outpatient and emergency prescriptions in our hospital is improving gradually, but further hard work should be carried out to improve prescriptions, quality continuously.

Key words: Cortex Periplocae different components, hepato-toxicity, oxidative damage mechanism