Abstract: Objective To investigate and analyze the prophylactic usage of antimierobial in perioperative period in our hospital in order to provide references for rationl use of anrimierobial in the clinic. Methods Unifed questionnaire was filled by clinieal pharmacists. In this retrospective survey, 200 medical charts of inpatients who discharged from five surgieal departments in our hospital from June to December in 2009 were seleeted randomly. The use of antimierobial was anaed statistieally. Results96.0% of the total 200 cases receiced antibacterials for prophhylaxis purpose for 6.5 days on average. Rational rate for the use of antimierobial was 59.0%, 23.0% received combination of two drugs, 6.0% received com bination of three drugs, 0.3% received combination of four drugs. Conclusion The usage rate of antimierobial was high in preioperative peried, the high class antibioties was used, the timing and duration of prophylactic use of drugs tends to be on the long side and execed the duration of antlbiotics instruetion principle in some cases. Therefore, intervention is urgenily needed toraekle these problems.

Key words: perio prariveperiod, antibaeterials, rational drug-use