Data mining and network analysis of Xiyanping injection in the treatment of viral intestinal infection based on the real world

doi:10.19803/j.1672-8629.2022.02.01

Abstract

Abstract: Objective To analyze the way in which Xiyanping injection is used in the treatment of viral intestinal infections so as to guide clinical rational medication. Methods Based on the hospital information management system (HIS) database constructed by the Institute of Clinical Basic Medicine of Chinese Academy of Traditional Chinese Medicine, the clinical data on 1 814 patients with intestinal infections treated with Xiyanping injection in 29 hospitals between December 1, 2006 and June 30, 2016 was analyzed; and the patterns of combined medications were studied. The data was processed with the Tabu search algorithm. Results The most frequently used western medicine was oral rehydration salt, compound vitamin, cimetidine and antibiotics. The most frequently used traditional Chinese medicine was antipyretic, astringent and antipyretic antidote. Conclusion In the treatment of viral intestinal infections, Xiyanping injection is often combined with vitamins, oral rehydration salt or with antipyretic antidotes and astringents to combat viruses, cure diarrhea, adjust the gastrointestinal environment and provide symptomatic treatment.

Key words: real world, Xiyanping injection, viral intestinal infection, complex network

CLC Number:

R932R975

JI Hong, WANG Zhifei, XIE Yanming, LI Lixun, WEI Ruili, WANG Qi. Data mining and network analysis of Xiyanping injection in the treatment of viral intestinal infection based on the real world[J]. Chinese Journal of Pharmacovigilance, 2022, 19(2): 117-120.

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