Water Retention and Neuropsychiatric Symptoms Induced by SAN AO PIAN

doi:10.19803/j.1672-8629.2020.10.18

Chinese Journal of Pharmacovigilance ›› 2020, Vol. 17 ›› Issue (10): 732-734.
DOI: 10.19803/j.1672-8629.2020.10.18

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Water Retention and Neuropsychiatric Symptoms Induced by SAN AO PIAN

CAO Jianying, WANG Xiao, SONG Yuhuan, FENG Zhanqin, QU Xiujun^*

Department of Pharmacy, Weifang Maternal and Child Health Hospital, Weifang Shandong 261011, China

Received:2020-10-14 Revised:2020-10-14 Online:2020-10-15 Published:2020-10-13

Abstract

Abstract: Objective To analyze the safety risk of water retention and neuropsychiatric symptoms induced by SAN AO PIAN (tablets). Methods The risk signals of one case of adverse reactions induced by SAN AO PIAN were reported while the causes were analyzed. Related databases were searched to mine ADR data about ephedra and ephedra-containing drugs that was published between January 2000 and July 2019. Results The adverse reactions induced by SAN AO PIAN were related to ephedra it contained and contraindications. Ephedrine, the main component of ephedra, can excite the central and sympathetic nerves, cause bladder sphincter contraction and detrusor relaxation, and induce neuropsychiatric symptoms and dysuria. Conclusion Clinicians should be alert to the adverse drug reactions caused by SAN AO PIAN, especially in patients with ephedra allergies. Clinical treatment should be provided in conjunction with syndrome differentiation to promote safe and rational use of drugs.

Key words: SAN AO PIAN, ephedra, neuropsychiatric symptoms, water retention

CLC Number:

R994.11

CAO Jianying, WANG Xiao, SONG Yuhuan, FENG Zhanqin, QU Xiujun. Water Retention and Neuropsychiatric Symptoms Induced by SAN AO PIAN[J]. Chinese Journal of Pharmacovigilance, 2020, 17(10): 732-734.

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Water Retention and Neuropsychiatric Symptoms Induced by SAN AO PIAN

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