Abstract: Objective To analyze the characteristics of adverse reactions of iodine contrast media in CT-enhanced scanning, so as to provide reference for clinical medication. Methods A retrospective analysis was performed on the data of patients with adverse reactions of iodine contrast media used in the CT Room of our hospital between January 2017 and May 2018. The gender, age, types of iodine contrast media, time of adverse reactions, systems involved and clinical manifestations of the patients were statistically analyzed. Results Among the 2 500 patients who received iodine contrast media during CT-enhanced scanning,81 (3.24%) ended up with adverse reactions, of whom 35 were males and 46 were females. The ratio of males to females was 0.76:1. Such commonly used non-ion iodinated agents as iopromide, iohexol, iodixanol and ioversol were involved, and iopromide and iohexol were responsible for most of the cases of adverse reactions. 27 cases occurred during the skin test, and 54 cases occurred after intravenous administration .The clinical manifestations of the anaphylactic reactions varied. Skin and its accessories disorders, such as rashes and pruritus, were the most common, followed by gastrointestinal disorders such as nausea and vomiting. Anaphylactic shock was the most serious but no death occurred. Conclusion Before using the media, we should pay attention to the prevention of adverse reactions and be prepared for any emergency, observe closely, identify adverse reactions and intervene early so as to improve the safety of clinical use of iodine contrast media.

Key words: CT enhandced scan, iodic contrast medium, adverse reaction, analysis