中国药物警戒 ›› 2012, Vol. 9 ›› Issue (3): 184-186.

• 药品不良反应监测 • 上一篇    下一篇

我院抗肿瘤及辅助治疗药物不良反应164例分析

刘加涛1，金亮2，汪燕燕1，周莹3，夏泉1   

  1. 1 安徽医科大学第一附属医院，安徽 合肥 230022；
    2 合肥市第三人民医院，安徽 合肥 230022；
    3 六安市第一人民医院，安徽 六安 237005
  • 收稿日期:2011-08-09 出版日期:2012-03-10 发布日期:2015-08-10
  • 作者简介:刘加涛，男，硕士研究生，临床药学。

An Analysis of 164 Cases of Anticancer and Supplementary Drugs Adverse Reactions

LIU Jia-tao1, JIN Liang2, WANG Yan-yan1, ZHOU Ying3, XIA Quan1   

  1. 1 The First Affiliated Hospital of Anhui Medical University, Anhui Hefei 230022, China;
    2 The Third People's Hospital of Hefei, Anhui Hefei 230022, China;
    3 The People's Hospital of Lu’an, Anhui Lu’an 237005, China
  • Received:2011-08-09 Online:2012-03-10 Published:2015-08-10

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摘要： 目的对我院肿瘤内科不良反应（ADR）的发生情况及特点进行分析，为临床合理用药提供参考。方法采用回顾性分类统计，对164例报告涉及的患者年龄、性别、给药途径药物类别以及临床表现进行分析。结果164例ADR中男性76例，女性88例;40岁以上154例;细胞毒类药物的发生率居首，占77.9%;ADR的临床表现以消化系统反应为主，其次为骨髓抑制。结论开展ADR监测工作是医务人员，特别是临床药师的重要任务，加强ADR监测，保障患者用药安全。

关键词: 抗肿瘤药物, 不良反应, 合理用药

Abstract: Objective To provide reference for clinical rational drug use, the tumor patients's adverse drug reacton(ADR) occurrence and characteristics in our hospital were analyzed. MethodsIn this paper, 164 cases of patients with anti-tumor drug adverse reaction reports were retrospective analyzed on the age, sex, administration way, drug classes and clinical manifestations. ResultsThe results showed that adverse drug reacton mainly happened in the 40 years and old tumor patients. Cytotoxic drugs take the highest incidence. The clinical manifestations of adverse drug reacton in gastrointestinal reaction is given priority, followed by bone marrow inhibition. ConclusionAdverse drug reacton monitoring and reporting work which ensure patients safely use their drugs is the medical staff, especially the clinical pharmacists important task.

Key words: antitumor drugs, adverse drug reacton, rational drug use