中国药物警戒 ›› 2012, Vol. 9 ›› Issue (3): 181-183.

• 药品不良反应监测 • 上一篇    下一篇

19例注射用双黄连（冻干）不良反应报告分析

林玲，冯昀熠*   

  1. 桂林市中医医院药剂科，广西 桂林 541002
  • 收稿日期:2011-08-18 出版日期:2012-03-10 发布日期:2015-08-10
  • 通讯作者: 冯昀熠,女,药师,新药开发与应用,临床药学。E-mail:fyyy123@yahoo.com
  • 作者简介:林玲，女，主管药师，临床药学。

Analysis on 19 Cases of Adverse Drug Reactions Caused by Shuanghuanglian Injection(Freeze-dried)

LIN Ling, FENG Yun-yi   

  1. Dept.of pharmacy, Guilin Traditional Chinese Medicine Hospital, Guangxi Guilin 541002, China
  • Received:2011-08-18 Online:2012-03-10 Published:2015-08-10

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摘要： 目的探讨注射用双黄连（冻干）所致不良反应的一般规律和特点，推动临床合理用药。方法我院2009年10月~2010年11月共有711例患者使用注射用双黄连（冻干），采用回顾性研究的方法，对发生不良反应的19例注射用双黄连（冻干）报告进行分析。结果注射用双黄连（冻干）的不良反应临床表现主要为皮疹、呕吐、胸闷等过敏反应，甚有1例过敏性休克。其不良反应的发生大多较快，多在注射过程中出现，在15~64岁年龄层发生率相对较高。结论注射用双黄连（冻干）的不良反应具有一定的规律性和特点，应据此合理应用。

关键词: 注射用双黄连（冻干）, 药品不良反应, 报告, 分析

Abstract: Objective To discuss the general pattern and characteristics of the adverse drug reactions(ADRs) induced by Shuanghuanglian injection(Freeze-dried) to provide guide for its rational use in the clinic. Methods711 patients used Shuanghuanglian injection(Freeze-dried) in our hospital from Oct.2009 to Nov.2010, a analysis was retrospectively investigated on 19 Shuanghuanglian injection(Freeze-dried) inducing ADR cases reported by this article. ResultsThe ADRs of Shuanghuanglian injection(Freeze-dried) were predominantly characterized by allergic reactions including skin rash、vomiting、chest distress, anaphylactic shock in 1 cases, most of the ADRs had quick onset and occurred in injecting, higher incidence in 15~64 age. ConclusionThe ADRs induced by Shuanghuanglian injection(Freeze-dried) assumed specific pattern and characteristics, therefore the rational use of Shuanghuanglian injection(Freeze-dried) should be emphasized.

Key words: Shuanghuanglian injection(Freeze-dried), adverse drug reactions, report, analysis