中国药物警戒 ›› 2014, Vol. 11 ›› Issue (8): 468-471.

• 质量与工艺研究 • 上一篇    下一篇

延生胶囊的薄层色谱鉴别及二苯乙烯苷的含量测定

马彧，宋瑩，杨荣艳*   

  1. 四平市食品药品检验所，吉林四平136000
  • 收稿日期:2016-02-03 修回日期:2016-02-03 出版日期:2014-08-08 发布日期:2016-03-02
  • 通讯作者: 杨荣艳，女，硕士，主管药师，中药材及中成药检验。E-mail:yry_lg@126.com
  • 作者简介:马彧，男，主任药师，药品检验及质量监督管理。

TLCIdentificationandHPLCDetermination of 2,3,5,4'-tetrahydroxystil bene-2-O- -D-glucosde in Yansheng Capsules

MAYu SONGYing YANGRong-yan*   

  1. SipingCity Institute for Food andDrug Control, Jilin Siping 136000,China
  • Received:2016-02-03 Revised:2016-02-03 Online:2014-08-08 Published:2016-03-02

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摘要： 目的建立延生胶囊的薄层色谱鉴别及二苯乙烯苷的含量测定方法。方法用薄层色谱法（TLC）对当归、独活、羌活、川芎、防风、麻黄、制何首乌进行鉴别；用高效液相色谱法（HPLC）测定二苯乙烯苷的含量。结果薄层鉴别斑点清晰；二苯乙烯苷平均加样回收率为98.3%，RSD = 1.16%。结论该鉴别方法重现性好，专属性强；含量测定方法简便、准确，可用于延生胶囊的质量控制。

关键词: 延生胶囊, TLC 鉴别, HPLC 测定, 二苯乙烯苷

Abstract: Objective To establish identification and quantitative determination method of Yansheng capules. Methods TLC was employed to identify six crude herbal elements in Yansheng capules and the content of 2,3,5,4'-tetrahy-droxystil bene-2-O- -D-glucosde was determined by HPLC. Results The spot developed on TLC was fairly clear. The average recovery of 2,3,5,4'-tetrahydroxystil bene-2-O- -D-glucosde was 98.3% with RSD1.16%.Conclusion The identification method is repeatable and specific, and the quantitative determination method is sim-ple and accurate, which can be used for the quality control of Yansheng capsules.

Key words: Yansheng capsules, TLC identification, HPLC determination, 2,3,5,4'-tetrahydroxystil bene-2-O- -D-glucosde

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