中国药物警戒 ›› 2011, Vol. 8 ›› Issue (2): 111-112.

• 药品不良反应监测 • 上一篇    下一篇

地芬诺酯滥用文献及监测数据的分析

马军丽, 逄立艳, 王秀娟, 周立新, 张黎明   

  1. 北京市药品不良反应监测中心,北京 100024
  • 收稿日期:2015-08-27 修回日期:2015-08-27 出版日期:2011-02-10 发布日期:2015-08-27
  • 作者简介:马军丽,女,硕士,公卫医师,药物滥用监测。

Analysis of Document and Monitoring Data of Diphenoxylate Abuse

MA Jun-li, PANG Li-yan, WANG Xiu-juan, ZHOU Li-xin, ZHANG Li-ming   

  1. Beijing Center for ADR Monitoring, Beijing 10024, China
  • Received:2015-08-27 Revised:2015-08-27 Online:2011-02-10 Published:2015-08-27

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摘要： 地芬诺酯是哌替啶衍生物,药理作用与阿片类物质相似。近年来药物滥用监测数据显示,吸毒人员存在滥用地芬诺酯及过量使用导致中毒的问题,正常人群中也出现了滥用地芬诺酯的病例报道。本文对近年来地芬诺酯的滥用文献及监测数据进行初步阐述,旨在分析地芬诺酯的滥用趋势,促进公众合理使用,并为药品监管部门的监管提供信息支持。

关键词: 地芬诺酯, 滥用, 中毒, 监测数据

Abstract: Diphenoxylate is a ramification of meperidine and has similar pharmacology reaction with opioid. Monitoring data of these years indicated that drug abuser did use diphenoxylate and overdose of diphenoxylate can lead to poisoning. There are also some case reports about diphenoxylate abuse in normal people. This paper tentatively introduced abuse document and monitoring data of diphenoxylate in order to reveal abuse tendency and to promote intelligent use of this substance. Hoping this paper can provide some information for drug administration.

Key words: diphenoxylate, abuse, poisoning, monitoring data

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