中国药物警戒 ›› 2024, Vol. 21 ›› Issue (5): 513-518.
DOI: 10.19803/j.1672-8629.20240196

• 阿片类药物合理使用专栏 • 上一篇    下一篇

阿片类药物全球滥用的监管现状及研究进展

李文鹏, 刘明煜, 曹颖, 周虎子威, 王胜锋*   

  1. 北京大学公共卫生学院,重大疾病流行病学教育部重点实验室(北京大学),北京 100191
  • 收稿日期:2024-03-26 出版日期:2024-05-15 发布日期:2024-05-13
  • 通讯作者: *王胜锋,男,博士,研究员,药物流行病、真实世界数据分析和大数据建模。E-mail: shengfeng1984@126.com
  • 作者简介:李文鹏,男,在读本科,预防医学。Δ为并列第一作者。
  • 基金资助:
    国家自然科学基金资助项目(82173616)

Supervision status and research progress of global abuse of opioids

LI Wenpeng, LIU Mingyu, CAO Ying, ZHOU Huziwei, WANG Shengfeng*   

  1. Peking University School of Public Health, Key Laboratory of Epidemiology of Major Diseases (Peking University), Ministry of Education, Beijing 100191, China
  • Received:2024-03-26 Online:2024-05-15 Published:2024-05-13

摘要: 目的 梳理阿片类药物全球滥用的监管现状及研究进展,为促进药物合理使用,改善滥用者治疗提出建议。方法 系统检索中国知网、万方数据、PubMed、国际麻醉品管制局、联合国毒品和犯罪问题办公室等网站有关文件,对纳入文献进行汇总和分析。结果 当前国际阿片类药物滥用情况仍不容乐观,目前以国际麻醉品管制局为首的国际机构从政策立法、区域合作、生产交易、预防治疗四个维度提出有效建议并启动了相关行动,同时研究者也从政策、预测滥用风险、滥用者治疗等不同维度开展了相关研究。结论 目前阿片类药物的监管措施及研究无法满足当下阿片类药物的监管需求,未来仍需从加强药物有效监管、预测药物滥用风险、改善成瘾治疗方案等方面深入研究,进一步改善阿片类药物滥用现状。

关键词: 阿片类药物, 药物滥用, 监管措施, 合理用药, 滥用风险预测, 研究进展

Abstract: Objective To sort out the supervision status and research progress of global opioids abuse,and to promote the rational use of drugs and improve the treatment of abusers. Methods The related literature and documents from CNKI, Wanfang Data, PubMed, International Narcotics Control Board, United Nations Office on Drugs and Crime were searched and analysed. Result At present, the situation of global opioids abuse is still not optimistic.International institutions led by the INCB have put forward effective recommendations and launched relevant actions from four dimensions: policy legislation, regional cooperation, production transactions and prevention and treatment. In addition, researchers have also carried out relevant studies from different dimensions, such as related policies, abuse risk prediction, and treatment of abusers. Conclusion Current opioid supervision and research cannot meet the current needs of opioids regulation. In the future, in-depth research is still needed from the aspects of strengthening effective drug regulation, predicting drug abuse risk, improving addiction treatment programs, etc., to further improve the current situation of opioid abuse.

Key words: opioids, drug abuse, supervision measures, rational drug use, abuse risk prediction, research progress

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