中国药物警戒 ›› 2011, Vol. 8 ›› Issue (10): 627-628.

• 药品不良反应监测 • 上一篇    下一篇

比索洛尔致不良反应文献分析

陈崇泽, 蒋秀焰   

  1. 福建省长乐市医院药剂科,福建 长乐 350200
  • 收稿日期:2010-08-06 出版日期:2011-10-10 发布日期:2015-07-30
  • 作者简介:陈崇泽,男,药师,药品不良反应监测。

Literature Analysis of Adverse Drug Reactions Induced by Bisoprolol

CHEN Chong-Ze, JIANG Xiu-Yan   

  1. Department of Pharmacy, Fujian Changle Hospital; Fujian Changle 350200, China
  • Received:2010-08-06 Online:2011-10-10 Published:2015-07-30

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摘要： 目的 探讨比索洛尔致不良反应的一般规律与特点。方法 检索中国期刊全文数据库及维普中文科技期刊文献数据库,收集1994~2009 年比索洛尔所致不良反应文献,并进行统计、分析。结果 比索洛尔引起的不良反应共计13例,男性多于女性。所致不良反应最多为窦房、房室阻滞5例（38.46 %）,其次为继发性闭经2例（15.38%）、泌尿系统疾病2例（18.36%）、呼吸系统障碍2例（18.36%）、神经系统问题1例（7.70%）。结论 临床上应加强比索洛尔应用的监测,以减少不良反应的发生。

关键词: 比索洛尔, 不良反应, 文献分析

Abstract: Objective To investigate the adverse effects of bisoprolol induced the general rules and characteristics. Methods We searched the "China Journal Full-text Database"and"Chinese Scientific and Technial Periodicals Database" in 1994 and 2009 due to adverse drug reactions bisoprolol, and statistical analysis. Results Bisoprolol caused a total of 13 cases of adverse reactions, more men than women. Adverse reactions due to a maximum of sinoatrial, atrioventricular block in 5 patients(38.46%), followed by secondary amenorrhea in 2 cases(15.38%), urinary system diseases in 2 cases(18.36%), respiratory disorder in 2 cases(18.36 %), neurological problems and 1(7.70%). Conclusion The clinical application should strengthen monitoring of bisoprolol in order to reduce the incidence of adverse reactions.

Key words: Bisoprolol, adverse reactions, literature analysis

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