华法林与中草药的相互作用

中国药物警戒 ›› 2011, Vol. 8 ›› Issue (1): 41-45.

华法林与中草药的相互作用

张彦丽, 王景红, 顾媛媛, 桂玥

北京中医药大学东方医院,北京100078

收稿日期:2010-07-20 出版日期:2011-01-10 发布日期:2015-08-24
作者简介:张彦丽,女,主管药师,临床药学。

The Drug Interactions with Warfarlin and the Traditional Chinese Medicines

ZHANG Yan-li, WANG Jing-hong, GU Yuan-yuan, GUI Yue

Dongfang Hospital Beijing University of Traditional Chinese Medicin, Beijing 100078, China

Received:2010-07-20 Online:2011-01-10 Published:2015-08-24

摘要/Abstract

摘要： 目的综述国内外报道华法林与常用中草药相互作用的相关文献,为临床安全应用华法林提供参考。方法查阅近年来国内外学者对于华法林与常用中草药相互作用的研究情况及可能的发生机制,进行归纳分析。结果部分中草药会影响华法林的抗凝作用,如当归、鹿衔草、大蒜等。结论多种中草药与华法林存在相互作用,提示在临床应用华法林的同时,重视中草药对抗凝作用的影响,提高临床用药的有效性和安全性。

关键词: 华法林, 中草药, 药物相互作用

Abstract: Objective To summarize the drug interactions with warfarlin and the traditional chinese medicines at home and abroad, it provided reference for clinical medication. Methods The related articles in recent years on the development and the occurrence mechanism of drug interactions with warfarlin and the traditional chinese medicines are extensively reviewed． Results Some traditional chinese medicines can alter the anticoagulation effect of warfarlin such as angelica sinensis, pyrola, garlic, et al. Conclusion The drug interactions were existed between warfarlin and the traditional chinese medicines. Pay attention to the effect of the traditional chinese medicines with the prescription of warfarlin, in order to improve the safety and effectiveness for clinical medication.

Key words: warfarlin, the traditional chinese medicines, drug interactions

中图分类号:

R916.2

张彦丽, 王景红, 顾媛媛, 桂玥. 华法林与中草药的相互作用[J]. 中国药物警戒, 2011, 8(1): 41-45.

ZHANG Yan-li, WANG Jing-hong, GU Yuan-yuan, GUI Yue. The Drug Interactions with Warfarlin and the Traditional Chinese Medicines[J]. Chinese Journal of Pharmacovigilance, 2011, 8(1): 41-45.

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