阿片类药物需要量的影响因素及干预措施研究进展

doi:10.19803/j.1672-8629.20240145

摘要/Abstract

摘要： 目的对阿片类药物需要量相关影响因素及干预措施进行综述,促进阿片类药物的合理使用。方法检索PubMed、中国知网、万方数据及有关文件,总结阿片类药物需要量影响因素及干预措施研究进展,归纳近年来加大合法用途阿片类药物供应的干预措施研究,总结现有研究经验和不足。结果现有研究主要关注临床措施、患者、社会三大层面的影响因素,存在不一致影响结果;但目前相关研究内容单一,且缺乏对不一致结果的探索,缺乏潜在影响因素及其机制研究;干预层面主要关注阿片类药物供应过程中各环节的干预措施,但目前仍缺乏对某一特定干预措施的研究。结论有关影响因素的研究,应进一步挖掘不一致结果的原因,从多因素联合分析、细化因素的测量维度、挖掘新的影响因素等角度深入;干预措施方面,应考虑关注干预措施的适用性研究、效果评价等。

关键词: 阿片类药物, 需要量, 影响因素, 干预措施, 疼痛管理

Abstract: Objective To summarize the existing literature on the influencing factors of opioid drugs, as well as the intervention measures for increasing the supply of legitimate opioid drugs in recent years. Methods The research progress on the influencing factors and intervention measures of opioid drug demand were analyzed by retrieving and screening data from PubMed, CNKI, Wan Fang, and relevant documents, Existing research experience and shortcomings are summarised. Results The influencing factors of clinical measures, patients, and society were summarized at three levels, but currently, relevant research only focuses on one possible influencing factor and lacks exploration of inconsistent results, correlation research, detailed research, and potential factor research; Summarize the intervention measures at each stage of the opioid drug supply process, but there is still a lack of specific research on a specific intervention measure. Conclusion In the future, research on the influencing factors of opioid drug demand can further explore the reasons for inconsistent results, from the perspectives of multi factor joint analysis, refining the measurement dimensions of factors, and exploring new influences; In terms of intervention measures, attention can be paid to the evaluation of their effectiveness and the study of their applicability.

Key words: opioids, requirements, influencing factors, intervention measures, pain management

中图分类号:

R971
R954

仇景辉, 周虎子威, 曹颖, 李文鹏, 王胜锋. 阿片类药物需要量的影响因素及干预措施研究进展[J]. 中国药物警戒, 2024, 21(5): 524-528.

QIU Jinghui, ZHOU Huziwei, CAO Ying, LI Wenpeng, WANG Shengfeng. Research progress on the influencing factors and intervention measures of opioid requirements[J]. Chinese Journal of Pharmacovigilance, 2024, 21(5): 524-528.

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