中国药物警戒 ›› 2019, Vol. 16 ›› Issue (9): 543-549.
DOI: 10.19803/j.1672-8629.2019.09.05

• 曲马多复方制剂滥用/使用调查研究专栏 • 上一篇    下一篇

曲马多复方制剂滥用/使用行为影响因素分析

于丹丹1, 孙骏1, 王佳域1, 吴晨2, 柳鹏程3,*   

  1. 1 江苏省药品不良反应监测中心,江苏 南京 210002;
    2 国家药品不良反应监测中心,北京100022;
    3 中国药科大学,江苏 南京211198
  • 收稿日期:2019-04-25 修回日期:2019-10-21 出版日期:2019-09-20 发布日期:2019-10-21
  • 通讯作者: *柳鹏程,男,在读博士,讲师,药品不良反应监测与药物滥用监测、药品价格、医保预算影响分析。E-mail:liupcmail@163.com
  • 作者简介:于丹丹,女,硕士,执业药师,药品不良反应监测与药物滥用监测。
  • 基金资助:
    国家药品不良反应监测中心资助项目(20178X006):曲马多复方制剂在吸毒人群中使用现状调查

Analysis of Factors Influencing Abuse/Use Behavior of Compound Tramadol

YU Dandan1, SUN Jun1, WANG Jiayu1, WU Chen2, LIU Pengcheng3,*   

  1. 1 Center for ADR Monitoring of Jiangsu, Jiangsu Nanjing 210002, China;
    2 National Center for ADR Monitoring, Beijing 100022, China;
    3 China Pharmaceutical University, Jiangsu Nanjing 211198,China
  • Received:2019-04-25 Revised:2019-10-21 Online:2019-09-20 Published:2019-10-21

摘要: 目的 了解曲马多复方制剂滥用/使用行为的影响因素,为防控滥用提供依据。方法 选取全国110所强制隔离戒毒所内药物滥用人员,58所强制隔离戒毒所内曲马多复方制剂滥用/使用人员为研究对象,采用Logistic回归分析方法分析曲马多复方制剂滥用/使用行为的影响因素。结果 中部地区、女性、首次滥用/使用年龄大、因易获得和戒毒而滥用/使用、考虑替代会增加滥用/使用曲马多复方制剂的可能性。结论 应强化对曲马多复方制剂的监控,重视曲马多复方制剂滥用/使用特点,针对高危人群,进行合理用药教育。建立药品追溯体系,完善药物监测系统。

关键词: 曲马多复方制剂, 药物滥用, Logistic回归分析, 影响因素

Abstract: Objective To analyze the influencing factors of the abuse/use of compound tramadol, with a view to providing evidence for prevention drug abuse. Methods A suvey was conducted among drug abusers from 110 compulsory isolated treatment centers and abusers/users of compound tramadol from 58 compulsory isolated treatment centers . Logistic regression analysis was used to explore the influencing factors of the abuse/use behavior of compound tramadol. Results Factors including central region, female, older age at first use, easy access, detoxification and consideration of substitution might increase the likelihood of abuse/use of compound tramadol. Conclusion We should emphasize the abuse/use characteristics of compound tramadol and strengthen the monitoring. Meanwhile, educate high-risk groups on rational use of compound tramadol. Establish the medication tracking system and improve the medication monitoring system.

Key words: compound tramadol, drug abuse, Logistic regression analysis, influencing factors

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