中国药物警戒 ›› 2021, Vol. 18 ›› Issue (3): 277-279.
DOI: 10.19803/j.1672-8629.2021.03.15

• 安全与合理用药 • 上一篇    下一篇

垂体后叶素注射液致严重腹泻1例分析

袁世加, 黄回, 杨欣, 方庆, 周杭*   

  1. 秀山土家族苗族自治县人民医院药学科,重庆 409900
  • 出版日期:2021-03-15 发布日期:2021-04-06
  • 通讯作者: *周杭,男,本科,主管药师,临床药学。E-mail: 767744130@qq.com
  • 作者简介:袁世加,男,本科,主管药师,药事管理和临床药学。

One Case of Severe Diarrhea Induced by Pituitrin Injection

YUAN Shijia, HUANG Hui, YANG Xin, FANG Qing, ZHOU Hang*   

  1. Department of Pharmacy, People's Hospital of Xiushan Tujia and Miao Autonomous County, Chongqing 409900, China
  • Online:2021-03-15 Published:2021-04-06

摘要: 目的 探讨垂体后叶素致腹泻的机制及高危因素,为临床合理使用垂体后叶素提供参考。方法 对1例垂体后叶素致严重腹泻患者进行分析,结合文献资料,提出预防和减轻腹泻的措施。结果 垂体后叶素致腹泻是新的严重不良反应,其用药剂量、患者年龄与腹泻程度有很大相关性。结论 通过调整给药方式、给药剂量以及联合用药等措施可以预防和减轻腹泻不良反应。

关键词: 垂体后叶素, 腹泻, 药品不良反应

Abstract: Objective To explore the mechanism and high-risk factors of diarrhea caused by pituitrin, and to provide reference for clinical rational use of pituitrin. Methods One case of severe diarrhea caused by pituitrin was analyzed. Combined with literature, the measures to prevent and alleviate diarrhea were proposed. Results Diarrhea caused by pituitrin is a new serious adverse reaction. The dosage and a patient's age are closely related to the severity of diarrhea. Conclusion The adverse reactions of diarrhea can be prevented and alleviated by adjusting the route of administration, dosage or via combination of drugs.

Key words: pituitrin, diarrhea, adverse drug reaction

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