Abstract: ObjectiveTo investigate the features of adverse drug reaction(ADR) induced by ornidazole sodium chloride injection in order to promote the safe drug use in clinic. MethodsThe ADR cases induced by ornidazole sodium chloride injection were searched between January 2011 and December 2012 in our hospital, and statistical analysis was made based on patients' basic characteristics, ADR time, clinical feature and drug use. ResultsThere were 54 ADR cases induced by ornidazole sodium chloride injection. The female cases were more than the males and patients' age was from 21 to 50 years old. The ADRs mostly occurred in the process of medication, mainly manifested as skin allergy, digestive reactions and phlebitis. There were 3 serious ADR cases, 21 cases had the combination of drug use, and no over-dose phenomenon. ConclusionThe patients treated with ornidazole sodium chloride injection should be closely monitored. The infusion should be scientifically arranged the sequence when multi-drugs are used so as to avoid potential hazards.

Key words: ornidazole sodium chloride injection, ADR, rational use of drugs