Analysis of Clinical Drug Event by HPLC and HPLC-MS

Chinese Journal of Pharmacovigilance ›› 2014, Vol. 11 ›› Issue (1): 54-56.

• Orignal Article • Previous Articles Next Articles

Analysis of Clinical Drug Event by HPLC and HPLC-MS

ZHOU Ning¹, GAO Jun^{1, *}, WANG Hong-liang², LI Lin²

1Beijing Bo-ai Hospital, Beijing 100068, China;
2Institute of Materia Medica, Chinese Academy of Medical Science, Beijing 100050, China

Received:2016-02-03 Revised:2016-02-03 Online:2014-01-08 Published:2016-02-03

Abstract

Abstract: ObjectiveTo analyze the color change event of omeprazole by pharmaceutical technology. MethodsThe contents of the mixed solution were determined using HPLC and HPLC-MS methods. ResultsThe result showed that omeprazole was mixed with ambroxolhydrochloride, which caused the color change reaction. No mixed solution was infused into the patient. ConclusionHPLC and HPLC-MS are applicable methods in the analysis of drug event. This study might serve as a reference for dealing with events alike.

Key words: HPLC, HPLC-MS, drug event

CLC Number:

R917

ZHOU Ning, GAO Jun, WANG Hong-liang, LI Lin. Analysis of Clinical Drug Event by HPLC and HPLC-MS[J]. Chinese Journal of Pharmacovigilance, 2014, 11(1): 54-56.

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Analysis of Clinical Drug Event by HPLC and HPLC-MS

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