Literature Analysis of Clinical Application and Adverse Drug Reaction/Event of Lianhua Qingwen Capsule

Abstract

Abstract: ObjectiveTo investigate and analyze the literatures on clinical application and ADR/ADE induced by Lianhua Qingwen Capsule to provide reference for its rational use in clinic. MethodsThe literatures for ADR/ADE of Lianhua Qingwen Capsule were retrieved in the databases of CNKI、Wangfang data for the last 10 years, which were screened out and analyzed by evidence-based medicine method and bibliometric statistical method. ResultsThirty-eight literatures were included and toltal 122 adverse drug reaction cases were collected. Most drug adverse reactions occurred after first use, primarily involved gastrointestinal system(73.9%), skin and its appendaes (9.6%), including nausea, vomiting, abdominal distention, diarrhea, skin rashes, itching, etc. ConclusionWe should reinforce the clinical application of Lianhua Qingwen Capsule, standardize and improve the drug package inserts, promote the rational use of drug and guarantee the safety of patients.

Key words: Lianhua Qingwen Capsule, clinical application, adverse drug reaction/event

CLC Number:

R979.21

PENG Li-li, LI Lan, SHEN Lu, LI Xing-ling. Literature Analysis of Clinical Application and Adverse Drug Reaction/Event of Lianhua Qingwen Capsule[J]. Chinese Journal of Pharmacovigilance, 2015, 12(12): 753-755.

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