Chinese Journal of Pharmacovigilance ›› 2012, Vol. 9 ›› Issue (3): 133-136.
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KANG A-long1, ZHANG-Xian1, TANG Ying-shuang2
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Abstract: Objective To study the Anti-inflammatory and Analgesic Activities of extracts of Daphnes Cortex and Daphnes Folium. Methods The anti-inflammatory effect was investigated by xylene-induced mice auricular swelling test and carrageenin-induced rat paw edema. Methods of acetic acid-induced writhing, hot-plate test in mice and tail-flick test were used to study the analgesic effect of Daphnes Cortex and Daphnes Folium. Results Daphnes Cortex and Daphnes Folium could reduce mice auricula swelling and rats foot-plate swelling. They could prolong the leg-licking time in mice provoked by hot-plate and inhibit acetic acid-induced-wring reaction in mice.It could obvious to improving the value of pain threshold in mice. Conclusion Daphnes Cortex and Daphnes Folium have a significant role in anti-inflammatory and analgesia. Daphnes Folium is more potent.
KANG A-long, ZHANG-Xian, TANG Ying-shuang. Study on the Anti-inflammatory and Analgesic Activities of Extracts of Daphnes Cortex and Daphnes Folium[J]. Chinese Journal of Pharmacovigilance, 2012, 9(3): 133-136.
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