TCM Medications for Pulmonary Nodules Based on Traditional Chinese Medicine Inheritance Assistance System

doi:10.19803/j.1672-8629.20241040

Abstract

Abstract: Objective To conduct data mining analysis of prescriptions for outpatients with pulmonary nodules using the Traditional Chinese Medicine Inheritance Assistance System (V2.5) in order to find out more about what medications are likely used. Methods Clinically effective TCM prescriptions for the treatment of pulmonary nodules were collected and screened before being input into the system for statistical analysis of the frequency of medications, properties of traditional Chinese medicines, and commonly-used compound formulas. Results A total of 609 effective traditional Chinese medicine prescriptions were screened out, and 31 types of TCMs were used more than 100 times. The analysis of properties of traditional Chinese medicines showed that the clinic mostly used cold and bitter medicines in the prescriptions, and most of the drugs targeted the lung and spleen meridians. The analysis of medications suggested that the core prescription proved to be Erchen decoction. The analysis of association rules showed that Bulb of Thunberg Fritillary and Pinellia Ternata were dominating in the prescriptions. The analysis of new compound formulas showed that there were five new combinations. Conclusion The pathogenesis of pulmonary nodules is usually attributed to the imbalanced middle energizer and to the combination of positiveness, deficiency, and phlegmatic toxin. It is recommended that pulmonary nodules be treated by regulating the spleen and stomach, strengthening qi and clearing phlegmatic toxin.

Key words: Pulmonary Nodules, Traditional Chinese Medicine Inheritance Support System, Data Mining, Erchen Decoction, TCM Compound Formulas, Patterns of Medication

CLC Number:

R969.3

LIU Lianlian, YU Huiyong, WANG Mingzhe, GUO Shanshan, LI Lei, GAO Yue, WEI Shixiang, KE Yinze, WANG Chengxiang. TCM Medications for Pulmonary Nodules Based on Traditional Chinese Medicine Inheritance Assistance System[J]. Chinese Journal of Pharmacovigilance, 2025, 22(5): 513-516.

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https://zgywjj.magtechjournal.com/EN/Y2025/V22/I5/513

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