Abstract: Objective To explore the existing problems of new pharmacopoeia in defining the toxicity degree, toxic ingredients, active ingredients, usage and dosage of toxic traditional Chinese medicine, analyze the influence of the existing problems on clinical application, and put forward some suggestions. Methods The existing problems of new pharmacopoeia in defining the toxicity degree, active ingredients ,toxic ingredients, usage and dosage of Chinese traditional medicine were analyzed by demonstration. Results The toxic traditional Chinese medicine’s toxicity, active ingredients, toxic ingredients, usage and dosage are lack of objective theory data and there is no unified standard. Conclusion It is necessary to strengthen the study on toxic traditional Chinese medicine pharmacology and toxicology, scientifically determine the toxicity degree, active ingredients and toxic ingredients of the toxic traditional Chinese medicines of raw products and processed products, and standardize the usage and dosage.

Key words: toxic traditional Chinese medicine, toxicity, usage and dosage, pharmacopoeia