To compare the quality of Schisandra formula particles from different manufacturers

Chinese Journal of Pharmacovigilance ›› 2017, Vol. 14 ›› Issue (5): 278-282.

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To compare the quality of Schisandra formula particles from different manufacturers

CHANG Yun-feng^{1, *}, HAO Lei¹, ZHANG Xiao-jian¹, LI Xue-li¹, GAO Han¹, LI Jun-shan^{1, 2}

1.Shineway Pharmaceutical Group Ltd,Hebei Shijiazhuang 051430,China;
2 Hebei province engineering and technology research center for traditional Chinese medicine formula particles dispensing granule,Hebei Shijiazhuang 050090,China

Received:2017-07-12 Revised:2017-07-12 Online:2017-05-20 Published:2017-07-12

Abstract

Abstract: Objective Comparison and analysis of the quality of Schisandra formula particles produced by different manufacturers, provide the basis for the establishment of a unified quality control method .Methods According to the granular requirement by the 2015 edition of "Chinese pharmacopoeia" , determinating and comparing samples from five different manufacturers ,Including it’s properties, particle size, moisture content, melting, loading quantity, extract and content, drug induced wettability,fingerprint. and then investigating its quality. Results The properties, particle size, moisture content, melting, loading quantity from five different manufacturers formula particles all meets the requirement ,but there is a big difference in the extract and content, drug induced wettability,fingerprint. Conclusion There is a big difference in the quality of Schisandra formula particles from different manufacturers,so it is urgent that establish uniform quality standards for formula particles.

Key words: different manufacturers, Schisandra, formula particles, fingerprint, comparison and analysis

CLC Number:

CHANG Yun-feng, HAO Lei, ZHANG Xiao-jian, LI Xue-li, GAO Han, LI Jun-shan. To compare the quality of Schisandra formula particles from different manufacturers[J]. Chinese Journal of Pharmacovigilance, 2017, 14(5): 278-282.

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To compare the quality of Schisandra formula particles from different manufacturers

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