Abstract: Objective To investigate the role of intensive hospital monitoring in the adverse drug reactions (ADR) supervising among inpatients in respiratory department. Methods All in-hospital patients admitted to the two treatment groups of respiratory department from January to June in 2016 were selected as observation subjects. Two clinical pharmacists were dispatched to the two treatment groups to participate in the daily ward-rounds. Each patient’s basic information, primary disease, drug use and ADR occurrence were recorded detailedly, and the incidence of ADR among different age groups as well as ADR occurrence in those patients who use different kinds of drugs were analyzed and compared, according to the requirements of the intensive hospital monitoring method. Results A total of 1, 003 patients were enrolled in the study, of which 138 cases presented ADR, with an incidence of ADR 13.76%. The incidence of ADR (31.43 %, 11/35) in group over 80-year-old was significantly higher than that in other age groups (average P < 0.05). Twenty-seven drugs were associated with ADRs, and the top three categories were antibacterial drugs (8 species), anti-tumor drugs (6 species) and anti-tuberculosis drugs (4 species), accounting for 66.67 % of all ADRs. Conclusion By applying intensive hospital monitoring method in respiratory department, the incidence and clinical manifestations of ADR have been revealed in different diseases, different ages and different drug use. Thus, patients can receive targeted pharmaceutical care, so as to ensure the safety of medication.

Key words: intensive hospital monitoring, department of respiratory, adverse drug reaction（ADR)