Analysis of 121 Cases of Adverse Drug Reactions in Elderly Patients in Psychiatry

Abstract

Abstract: Objective To analyze the features of adverse drug reactions (ADRs) in the elderly people (>65 years old) , so as to provide basis for clinical drug monitoring.Methods We made a retrospective analysis on ADR reports in the elderly psychiatric patients (> 65 years old ). The reports were from the year 2004 to 2016.Results We collected 121 cases of ADR reports in the elderly psychiatric patients, 39 cases of men, and 82 cases of women, the average age (72.29±5.40), 67 kinds of drugs involved. Of psychotropic drugs, the mainly involved was antipsychotics (55.37%), followed by antidepressants (18.18%). Oral in take was the main route of administration (90.91%). ADR damage mainly affected the nervous system (21.65%) and digestive system (18.56%), followed by mental disorders (14.43%).Conclusion Elderly patients with psychiatric drugs appear to have all sorts of ADR more easily. We should strengthen ADR monitoring of elderly patients, and promote rational drug use of clinic to improve the safety of drug use in elderly patients.

Key words: psychiatry, elderly patient, adverse drug reaction(ADR), retrospective analysis

CLC Number:

ZHUANG Hong-yan, LIU Shan-shan ,GUO Wei, MA Xin, HAO Hong-bing ,ZHANG Yi ,NIU Song. Analysis of 121 Cases of Adverse Drug Reactions in Elderly Patients in Psychiatry[J]. Chinese Journal of Pharmacovigilance, 2017, 14(2): 105-108.

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