Abstract: Objective The effective ingredients of for anti-anaphylaxis were preliminarily confirmed by compare with the different components' antiallergic effects, in order to provide references and research ideas for innovative drugs. Methods The mice's anti-permeability strengthening of allergenic capillary vessels and passive anaphylaxis of the skin to select the effective ingredients of for anti-anaphylaxis were preliminarily observed after given alcohol extract、water extract and volatile oil components to compare with the different components' antiallergic effects.Results The antiallergenic effect of alcohol extract was the most effective, and the water extract and volatile oilcomponents were inferior which had no obvious difference between the latter two groups, and there were obviousdifferences of the antiallergenic effect between the alcohol extract and water extract or volatile oil components by compareing the antiallergenic effect of different extract of Flos Magnolia. Conclusion The antiallergenic activity ofthe different ingredients from Flos Magnolia were alcohol extract >water extract>volatile oil components, and under the guidance of antiallergenic activity, the effective ingredients of was the alcohol extract. But as the Flos Magnolia complex of pharmacodynamics characteristics of TCM and the interaction between the components and molecular mechanisms of Flos Magnolia were not very clear, so it is necessary to take more research of the multi-components between the pharmacological and molecular mechanisms, in order to provide references and research ideas for inno-vative drugs.

Key words: Flos Magnolia , different components, anti-anaphylaxis