Abstract: Objective To establish a method for quantitative determination of schisandrin in baojing granule. Methods HPLC was used. The samples were separated ona kromasil C18 column(250mm伊4.6mm,5μm) witha mobile phase of acetonitrile and water( 45:55,v/v) , pumped at the flow rate of 1.0 mL·min ^-1 and detected at 250 nm. Results The result showed that the average recovery of schisandrin was 100.7% (RSD=1.3% , n=6). Conclusion The method hasa good specificity and stability, which can be applied to the quality control of baojing granule.

Key words: baojing granule, schisandrin, RP-HPLC, assaying