Chinese Journal of Pharmacovigilance ›› 2014, Vol. 11 ›› Issue (12): 757-759.

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Experimental Study on the Drug Absorptivity of Medical Disposable PVC Connection Tube

ZHOU Jin2, CHENG Yun-zhang1, *, LUO Wen-xiang1   

  1. 1School of Medical and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China; 2Jiangsu Food and Drug Administration, Jiangsu Yangzhou 225261, China
  • Received:2014-03-31 Revised:2016-02-03 Online:2014-12-08 Published:2016-03-02

Abstract: ObjectiveTo investigate the absorptivity of medical disposable PVC connection tube to various drugs, as a reference for clinical choice of disposable PVC connection tube. MethodsSolution of 6 kinds of drugs, such as nitroglycerin, nimodipine and isosorbide mononitrate,were prepared separately as per actual concentration needed by the clinic. Drug concentrations before and after through the connection tube were measured by absorbance experiment and eventually calculated absorption rate of 6 kinds of drugs in different time. ResultsThe various drugs have different absorption rate and nimodipine gets a rather high value which can be up to 29.6%. ConclusionThe absorptivity of PVC connection tube has little relation to acid-base property. They have marked absorptivity to part of drugs. High attention from the clinic should be paid to the difference.

Key words: PVC connection tube, absorbance, drug absorptivity

CLC Number: