Research Progress in the Role of Molecular Hydrogen in the Treatment of Periodontal Diseases

doi:10.19803/j.1672-8629.20250937

Abstract

Abstract: Objective To explore the mechanisms and administration methods of molecular hydrogen (H₂) and to summarize the research progress in the treatment of periodontal diseases with H₂. Methods Related literature was reviewed to summarize the molecular mechanisms and routes of administration of H₂ as well as the current applications and therapeutic effects of H₂ in the treatment of periodontal diseases. Results H₂ possessed significant antioxidant, antiinflammatory, and anti-apoptotic properties. Clinically, the consumption of hydrogen-rich water could effectively facilitate the treatment of periodontal diseases. Conclusion H₂ promises good potential in the prevention and treatment of periodontal disease. However, more in-depth studies are required to establish its efficacy and safety.

Key words: Molecular Hydrogen (H₂), Periodontal Disease, Administration Methods, Antioxidant, Anti-Inflammatory, Mechanism

CLC Number:

R988.2
R961

YU Fengxin, DAI Chunli, JIA Sen. Research Progress in the Role of Molecular Hydrogen in the Treatment of Periodontal Diseases[J]. Chinese Journal of Pharmacovigilance, 2026, 23(5): 595-599.

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https://zgywjj.magtechjournal.com/EN/Y2026/V23/I5/595

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