Chinese Journal of Pharmacovigilance ›› 2017, Vol. 14 ›› Issue (11): 646-652.

Previous Articles     Next Articles

Acquisition and Analysis of Basic Data of Juvenile Bama Miniature Pigs

GUO Xin-miao1, WANG Ying1, MENG Ye1, YU Yang1, ZHOU Liang1, WANG Can2, FAN Xiao-yu2, JIN Hong-tao1,2, WEI Jin-feng1,2,*   

  1. 1 Beijing Union-Genius Pharmaceutical Technology Development Co., Ltd., Beijing 100176, China;
    2 New Drug Safety Evaluation Center, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
  • Received:2017-12-26 Revised:2017-12-26 Online:2017-11-20 Published:2017-12-26

Abstract: Objective To acquire and analyze the basic data of different day old juvenile Bama miniature pigs, the data mainly include body weight, body length, body temperature, electrocardiograph data, hematological index, blood biochemical indexes, blood coagulation indexes, immunological indexes, urine indexes, tibia length, organ weight and organ coefficient. Methods The 30 juvenile Bama miniature pigs (15 females and 15 males) were fed and managed normally in this experiment. The body weight, body length, body temperature were measured between 8~64 days old every 7 days. The electrocardiograph data were collected at 7, 35, 63 days old. The hematological index, blood biochemical indexes, blood coagulation indexes, T cell subsets and tibia length were measured at 36, 64 days old. 18 Bama miniature pigs (9 females and 9 males) were killed at 36 days old and the other 12 Bama miniature pigs (6 females and 6 males) were killed at 64 days old to measure the organ weight and organ coefficient. The mean value and standard deviation were calculated using SPSS software. Results and Conclusion The research established the basic data of physiological indexes of juvenile Bama miniature pigs at different days old, these data may be helpful to the research of juvenile Bama miniature pigs.

Key words: juvenile Bama miniature pig, experimental animal, basic data

CLC Number: