Researches about the Relationship between Rotavirus Vaccine and Intussusception

Abstract

Abstract: Rotavirus is the main cause of diarrheal illness among children. In developed countries, it's a huge financial burden of emergency and hospitalization due to rotavirus infection. In developing countries, it's the main reason to children death. Vaccination is one of the effective Methods to prevent the disease. The first vaccine, RotaShield, was withdrawn from the market in 1999 because it was suspected to increase the risk of intussusception in recipients. In 2006, the new vaccine, RotaTeq and Rotarix, were introduced to the market. The relationship between rotavirus vaccine and intussusception is still the hot topic. There are still no changes of immunization program about rotavirus vaccine in the world.In the paper, the researches about rotavirus vaccine and intussusception are summarized.

Key words: rotavirus, rotavirus vaccine, intussusception

CLC Number:

WANG Ya-li,DONG Duo. Researches about the Relationship between Rotavirus Vaccine and Intussusception[J]. Chinese Journal of Pharmacovigilance, 2015, 12(4): 241-244.

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