Abstract: Objective To observe the clinical effect of self-made Geche decoction for the treatment of infantile rotavirus enteritis (IRE). Methods All 90 patients are randomly divided into three groups, Routine medication group (group A), ribavirin group (group B) and Geche decoction group (group C), 30 cases in each group. Group A was given zinc gluconate tablets and oral rehydration salts Ⅲ (ORS Ⅲ) everyday. Group B was based on group A to plus ribavirin injection. Group C was based on group A to plus Geche decoction. All of the groups were given 7 days treatment. Results The total effective rate was 63.3% in group A, 60.0% in group B and 90.0% in group C, respectively, showing significant difference (P<0.05) in comparing group C with group A and B. After 6 days of treatment, the negative conversion rate of rotavirus was 43.3% in group A, 56.7% in hroup B and 83.3% in group C, respectively, which was higher in group A than group A and B(P <0.05). Conclusion Self-made Geche decoction could effectively alleviate the clinical symptoms and signs in IRE patients, accelerate the negative conversion of rotavirus. So it is an effective drug for IRE in treatment TCM.

Key words: Traditional Chinese Medicine and Traditional Chinese Herb, Geche decoction, rotavirus, enteritis