Chinese Journal of Pharmacovigilance ›› 2014, Vol. 11 ›› Issue (3): 151-153.

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Advance Research on Pharmacological Effect and Toxicity of Senecio Scandens

FENG Qun1, 2, LI Xiao-yu1, SUN Rong1, *   

  1. 1Shandong Research Academy of TCM, Shandong Jinan 250014, China;
    2Tianjin University of Traditional Chinese Medicine, Tianjin 300073, China
  • Received:2012-09-09 Revised:2016-02-03 Online:2014-03-08 Published:2016-02-03

Abstract: ObjectiveTo provide literature basis and idea for the research of relevance between efficacy, material basis and toxicity of Senecio scandens. MethodsAncient books, literature in past dynasties and references in the last decades at home and abroad about the efficacy and toxicity of Senecio scandens were collated, analyzed and summarized. ResultsThe efficacy of Senecio scandens is mainly antibacterial, antioxidative, antiviral, antineoplastic and so on. Also the toxicity of it includes hepatotoxicity, skeletal dysplasia, mutagenesis, etc. ConclusionThe toxicity of Senecio scandens should be researched in the process of efficacy-expression. Basis would be provided for consummating safety standards and putting forward early-warning scheme of adverse reaction that can be referred in clinic. In this way Senecio scandens can be ensured to use safely.

Key words: Senecio scandens, pharmacological effect, toxic characteristic

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