中国药物警戒 ›› 2024, Vol. 21 ›› Issue (8): 946-948.
DOI: 10.19803/j.1672-8629.20240066

• 安全与合理用药 • 上一篇    下一篇

稳心颗粒致持续性呃逆1例分析

郭海嬿1, 何波2, 闫鸿丽3, 杨雪婷4,*   

  1. 1大理大学药学院,云南 大理 671000;
    2昆明医科大学药学院,云南省天然药物药理重点实验室,云南 昆明 650500;
    3云南中医药大学药剂教研室,云南 昆明 650500;
    4云南省第一人民医院,昆明理工大学附属医院药学部,云南 昆明 650032
  • 收稿日期:2024-01-25 出版日期:2024-08-15 发布日期:2024-08-21
  • 通讯作者: *杨雪婷,女,硕士,副主任药师,临床药学。E-mail:374095634@qq.com
  • 作者简介:郭海嬿,女,硕士,临床药学。
  • 基金资助:
    国家自然科学基金资助项目（81860665）; 云南省科技厅科技计划项目（202101AZ070001-036）; 云南省第一人民医院临床医学研究中心开放项目（2023YJZX-YX24）

One case of persistent hiccup caused by Wenxin Keli

GUO Haiyan1, HE Bo2, YAN Hongli3, YANG Xueting4,*   

  1. 1College of Pharmacy Dali University, Dali Yunnan 671000, China;
    2School of Pharmacy, Kunming Medical University, Key Laboratory of Natural Drug Pharmacology of Yunnan Province, Kunming Yunnan 650500, China;
    3Department of Pharmacy, Yunnan University of Chinese Medicine, Kunming Yunnan 650500, China;
    4Department of Pharmacy, the First People’s Hospital of Yunnan Province/the Affiliated Hospital of Kunming University of Science and Technology, Kunming Yunnan 650032, China
  • Received:2024-01-25 Online:2024-08-15 Published:2024-08-21

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摘要： 目的 对稳心颗粒引起持续性呃逆新的不良反应进行分析。方法 分析1例28岁女性服用稳心颗粒后出现持续性呃逆,评价持续性呃逆与怀疑药物的相关性,并通过文献回顾分析稳心颗粒导致患者持续性呃逆的原因及机制。结果 经关联性评价,本例呃逆不良反应很可能因稳心颗粒所致。采用停药措施,患者未再发生持续性呃逆症状。结论 稳心颗粒可致持续性呃逆的不良反应,医务人员应提高警惕,加强对其不良反应的监测。

关键词: 稳心颗粒, 呃逆, 药品不良反应

Abstract: Objective To analyze the new adverse reaction of Wenxin Keli causing persistent hiccups. Methods A case of persistent hiccups in a 29-year-old woman taking Wenxin Keli was analyzed. The relevance of persistent hiccups to the suspected drug was evaluated, and the causes and mechanisms of persistent hiccups in the patient caused by Wenxin Keli were analyzed through a literature review. Results By correlation evaluation, this case of hiccup is most likely due to Wenxin Keli. Discontinuation measures were used, and the patient did not experience further symptoms of persistent hiccups. Conclusion Medical personnel should be vigilant and strengthen the monitoring of the adverse reaction of Wenxin Keli causing persistent hiccups.

Key words: Wenxin Keli, hiccup, adverse drug reaction

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