中国药物警戒 ›› 2016, Vol. 13 ›› Issue (7): 433-436.

• 安全性评价与合理用药 • 上一篇    下一篇

临床药师干预对复方氨基酸（15）双肽（2）注射液应用的影响分析

朱愿超, 梁良, 赵明, 杨莉萍   

  1. 北京医院药学部药物临床风险与个体化应用评价北京市重点实验室，北京 100730
  • 收稿日期:2016-02-04 修回日期:2018-07-17 出版日期:2016-07-20 发布日期:2018-07-17
  • 通讯作者: 杨莉萍，女，博士，主任药师，药物相互作用、循证药学、药物基因组学。E-mail：yczhu-2009@163.com
  • 作者简介:朱愿超，女，硕士，主管药师，临床合理用药与老年病学。

Effects of Pharmaceutical Intervention on Rational Clinical Use of Compound Amino Acids (15) and Dipeptides (2) Injection

ZHU Yuan-chao, LIANG Liang, ZHAO Ming, YANG Li-ping   

  1. Department of Pharmacy, Beijing Hospital, Assessment of Clinical Drugs Risk and Individual Application Key Laboratory, Beijing 100730, China
  • Received:2016-02-04 Revised:2018-07-17 Online:2016-07-20 Published:2018-07-17

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摘要： 目的 调查临床药师对复方氨基酸（15）双肽（2）注射液合理使用的干预效果。方法 查阅全院2014年12月使用复方氨基酸（15）双肽（2）注射液的出院病历以获取基线数据，针对发现的问题实施一系列药学干预。再次查阅2015年3月全院使用复方氨基酸（15）双肽（2）注射液的出院病历，比较和分析两组病历的使用差异。结果 实施药学干预后，氨基酸（15）双肽（2）注射液消耗金额占总药品消耗金额的比例由0.98%降至0.45%（P< 0.05），在符合用药适应证、正确选择用药途径等方面也比干预前有显著改善（P<0.05）。结论 临床药师干预对复方氨基酸（15）双肽（2）注射液的合理使用产生显著的有益影响。

关键词: 复方氨基酸（15）双肽（2）注射液, 药学干预, 合理用药

Abstract: Objective To evaluate the effects of pharmaceutical intervention on the rational use of compound amino acids (15) and dipeptides (2) injection. Methods Patients who received treatment with compound amino acids (15) and dipeptides (2) injection in Dec 2014 were checked to obtain baseline data. A series of pharmaceutical interventions were carried out. Then data from patients who received therapy with this drug in May 2015 were collected once again. The differences before and after the intervention were compared and analyzed. Results The consumption ratio of compound amino acids (15) and dipeptides (2) injection was reduced from 0.98% to 0.45% (P < 0.05). The rates of correct indication, correct route of administration after the intervention were significantly higher than those before the intervention (P <0.05). Conclusion Pharmaceutical intervention has a significant beneficial impact on the rational use of compound amino acids (15) and dipeptides (2) injection in our hospital.

Key words: compound amino acid (15) and dipeptides (2) injection, pharmaceutical intervention, rational drug use

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