中国药物警戒 ›› 2010, Vol. 7 ›› Issue (3): 168-171.

• 药品不良反应监测 • 上一篇    下一篇

371例门诊输液不良反应/事件分析

韦润莲, 蓝琼妮, 黄霜霞   

  1. 广西医科大学第一附属医院,广西 南宁 530021
  • 收稿日期:2009-03-05 修回日期:2016-02-19 出版日期:2010-03-08 发布日期:2016-02-19
  • 作者简介:韦润莲,女,主管药师,药房管理及用药咨询。

Analysis of 371 Adverse Drug Reaction /Event Cases Induced by Out-patient Injection

WEI Rui-lian, LAN Qiong-ni, HUANG Shuang-xia   

  1. The First Affiliated Hospital of Guangxi Medical University, Guangxi Nanning 530021, China
  • Received:2009-03-05 Revised:2016-02-19 Online:2010-03-08 Published:2016-02-19

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摘要： 目的 分析引起门诊输液不良反应/事件的各种因素,探讨控制输液不良反应/事件的措施。方法 对2003年6月~2008年6月我院门诊输液室发生的不良反应/事件病例进行统计分析。结果 371例不良反应/事件涉及药物56种,抗生素引发者最常见（185例,49.9％）,其次为中药注射剂（88例,23.7％）;发生不良反应/事件最短时间为5分钟,而10~30分钟有160例（43.1％）发生不适症状,是不良反应/事件发生的重要阶段;临床表现以皮肤及其附件损害为主。结论 门诊输液应建立严格的不良反应监测系统,针对引起不良反应/事件的因素采取相应的预防措施,控制输液不良反应的发生率。

关键词: 输液, 不良反应, 药学服务

Abstract: Objective To analyze the factors which cause the adverse drug reaction/event(ADR/ADE) induced by out-patient injection, and to explore how to control ADR/ADE. Methods ADR/ADE cases collected from the clinic injection room in our hospital have analyzed. Results There were 56 kinds of drugs related with 371 ADR/ADE, and antibiotics were in the first place(185 cases, 49.9%), followed by the Traditional Chinese Medicine injection(88 cases, 23.7%). The shortest time between infusion and ADR/ADE occurrence was five minutes, but 160 ADR/ADE cases (43.1%) occurred in 10~30 minutes after injection, so it is an important stage to inspect ADR/ADE. Lesions of the skin and the appendants is most. Conclusion To reduce the incidence of ADR/ADE induced by out-patient injection, our hospital should establish a strict ADR monitoring system, and take some preventive measures.

Key words: injection, adverse drug reaction/event(ADR/ADE), pharmacy services

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