中国药物警戒 ›› 2016, Vol. 13 ›› Issue (10): 614-618.

• 安全性评价与合理用药 • 上一篇    下一篇

1188例苯二氮卓类药物滥用监测数据分析

王亚丽1, 张倩婷2, 苑国辉3, 王力剑3, 曲毅3*, *   

  1. 1.国家食品药品监督管理总局药品评价中心,北京 100045;
    2.贵州省药品评价中心,贵州 贵阳 550004;
    3.吉林省食品药品安全监测中心,吉林 长春,130062
  • 收稿日期:2016-11-23 修回日期:2016-11-23 出版日期:2016-10-20 发布日期:2016-11-23
  • 通讯作者: 曲毅,女,博士,主管药师,药物滥用监测和药械安全性监测。E-mail：18043008190@163.com。
  • 作者简介:王亚丽,女,博士,药品不良反应监测与评价。

Analysis of Monitoring Data of 1188 Cases of Benzodiazepines Drug Abuse

WANG Ya-li1, ZHANG Qian-ting2, YUAN Guo-hui3, WANG Li-jian3, QU-Yi3, *   

  1. 1.Center for Drug Reevaluation, CFDA, Beijing 100045, China;
    2.Guizhou Province Center for Drug Reevaluation, Guizhou Guiyang 550004, China;
    3.Jilin Safety Monitoring Center for Food and Drug, Jilin Changchun 130062, China
  • Received:2016-11-23 Revised:2016-11-23 Online:2016-10-20 Published:2016-11-23

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摘要： 目的 通过对苯二氮?类药物滥用监测数据进行分析,判断吉林地区苯二氮?类药物滥用趋势,运用药物滥用的监测手段来反映此类人群各项特征。方法 检索《药物滥用监测网络信息管理系统》,分别以“吉林地区、2011~2015年、苯二氮?类”作为检索条件进行检索,并对检索数据进行列项分析。结果 2011~2015年,吉林地区共有1 188例报告涉及苯二氮?类药物滥用：滥用者主要集中在40岁以上;初中以上学历占83.8%,以无业和企业人员最多;滥用方式主要以口服为主;多从医院中获得药品;多数目的是缓解烦恼、抑制情绪;滥用时间最长大于15年。结论 2011~2015年之间的1 188例苯二氮?类药物滥用数据分析提示,此类人群一定要控制用药时间,以免剂量过大、时间过长形成苯二氮?类药物成瘾。

关键词: 苯二氮?类, 精神药品, 药物滥用, 吉林地区

Abstract: Objective To investigate the drug abuse trends of diazepam based on surveillance data while determine the features among these drug-abuse people via drug-abuse monitoring strategies. Methods Surveillance data between 2011 and 2015 was collected and analyzed by Information Management System of Drug Abuse Surveillance Network through using keywords of ‘Jilin region’ and ‘benzodiazepines’. Results 1 188 cases of benzodiazepine drug abuse from Jilin region were reported between 2011 and 2015 according to the drug abuse surveillance data. The drug abusers of benzodiazepines were mainly among people over 40 years old. Individuals with educational backgrounds over junior high school accounted for 83.8% of the drug abusers. Most of those were unemployed. Oral administration was the most common way for the intake of abused drugs normally attained from hospitals. The major purposes for drug abuses were to ease troubles and inhibit emotion. The longest duration for drug abuse could be more than 15 years. Conclusion It can be concluded from the surveillance data of benzodiazepine drug abuse between 2011~2015 that drug abusers need to control their dosages and medication time to prevent the drug addiction of benzodiazepines.

Key words: benzodiazepine, psychotropic drug, drug abuse, Jilin region

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