中国药物警戒 ›› 2014, Vol. 11 ›› Issue (8): 462-464.

• 基础与临床研究 • 上一篇    下一篇

活血化瘀方案对脑出血患者生活质量改善的影响

陈澈1, 院立新1, 李净娅2, 张根明3*   

  1. 1北京中医药大学第一临床医学院,北京 100029;
    2北京中医药大学第三临床医学院,北京 100029;
    3北京中医药大学东直门医院脑病科,北京 100700
  • 收稿日期:2016-02-03 修回日期:2016-02-03 出版日期:2014-08-08 发布日期:2016-03-02
  • 通讯作者: 张根明,男,博士,主任医师,中医药防治脑血管病研究。E-mail：13522973039@163.com
  • 作者简介:陈澈,女,在读硕士,中医药防治脑血管病研究。

Effect for Improving Living Quality of Intracerebral Hemorrhage with Blood-activating and Stasis-removing Therapy

CHEN Che1, YUAN Li-xin1, LI Jing-ya2, ZHANG Gen-ming3, *   

  1. 1The First Clinical Medical College Affiliated to Beijing University of Chinese Medicine, Beijing 100029, China;
    2The Third Clinical Medical College Affiliated to Beijing University of Chinese Medicine, Beijing 100029, China;
    3Department of Encephalopathy of Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing 100700, China
  • Received:2016-02-03 Revised:2016-02-03 Online:2014-08-08 Published:2016-03-02

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摘要： 目的观察活血化瘀方案对脑出血患者生活质量改善的影响。方法228例脑出血患者随机分为两组。对照组114例予内科基础治疗,试验组114例在此基础上予醒脑静注射液静脉滴注14天,辨证服用活血化瘀免煎颗粒21天,21天后口服脑血疏口服液至发病3个月。观察两组基于中风患者报告的临床结局（PRO量表）评分变化情况。结果试验组在入组第21天及3个月时PRO量表的生理功能、心理精神状态、社会关系和治疗满意度等指标总分均低于对照组（P<0.05）。且各单项指标分值在一些时点亦低于对照组（P<0.05）。结论活血化瘀方案可改善脑出血患者在发病后一定时期内的生活质量,对于提高脑出血的临床疗效有一定意义。

关键词: 脑出血, 活血化瘀, 生活质量, 临床观察

Abstract: ObjectiveTo observe the effect for improving living quality of intracerebral hemorrhage with blood-activating and stasis-removing therapy. MethodsA total of 228 cases with cerebral hemorrhage were randomly divided into the treatment group (n=114) and the control group (n=114). The control group was treated with the basic treatment of internal medicine. On the basis of it, the treatment group received intravenous infusion with Xingnaojing injection for 2 weeks and was given TCM granules for 21 days dynamically and dialectically. After these, the treatment group was asked to drink Naoxueshu oral liquid until the 3rd month of incidence. The clinical outcome assessment of patient reported outcomes(PRO) scores were observed in two groups. ResultsCompared with the first day, the treatment group PRO scores were superior to control group in 21th day and 3rd month after entering the group (P <0.05). And the single index in some time was also lower than the control group (P<0.05). ConclusionIntracerebral hemorrhage with blood-activating and stasis-removing therapy had an effective result in improving living quality in a certain period of time. It is good to improve the clinical efficacy.

Key words: intracerebral hemorrhage, blood-activating and stasis-removing method, living quality, clinical observation

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