中国药物警戒 ›› 2014, Vol. 11 ›› Issue (6): 366-368.

• 医院药事管理与合理用药 • 上一篇    下一篇

2951例病原菌的分布及其对常用抗菌药物的耐药分析

吕建华, 李改素, 李永兵   

  1. 濮阳市人民医院,河南 濮阳 457000
  • 收稿日期:2013-10-17 修回日期:2016-02-03 出版日期:2014-06-08 发布日期:2016-03-02
  • 作者简介:吕建华,女,本科,主管药师,医院药学

Distribution and Antimicrobial Resistance Analysis for Commonly Used Antibiotics of 2 951 Pathogens

LV Jian-hua, LI Gai-su LI, Yong-bing   

  1. Puyang People's Hospital, Henan Puyang 457000, China
  • Received:2013-10-17 Revised:2016-02-03 Online:2014-06-08 Published:2016-03-02

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摘要： 目的了解我院临床分离出的2 951例病原菌对常用抗菌药物的耐药性。方法对2 951株临床分离菌株进行药敏试验。结果临床分离菌株中革兰阳性菌占17.45%,革兰阴性菌占82.55%。革兰阳性球菌对万古霉素、利奈唑胺高度敏感;革兰阴性杆菌对头孢哌酮舒巴坦、哌拉西林他唑巴坦、亚胺培南和美罗培南敏感性较高。结论肠杆科大肠埃希菌耐药率高于肺炎克雷伯菌,非发酵菌的鲍曼不动杆菌、铜绿假单胞菌显示多重耐药。

关键词: 抗菌药物, 病原菌, 革兰阳性菌, 革兰阴性菌

Abstract: ObjectiveTo investigate the drug resistance of 2 951 pathogens for commonly used antibiotics. MethodsAntimicrobial susceptibility testing of 2 951 isolated bacteria was carried out. ResultsOf 2 951 clinical isolates gram-positive bacteria accounted for 17.45% and gram-negative bacteria accounted for 82.55%. Sensitivity of gram-positive cocci to vancomycin and linezolid was high; gram-negative bacilli showed higher sensitivity to cefoperazone sulbactam, piperacillin-tazobactam, imipenem and meropenem. ConclusionThe drug resistance rate of Escherichia coli was higher than Klebsiella pneumoniae; Acinetobacter baumannii and Pseudomonas aeruginosa display multiple drugs resistance.

Key words: anti-bacterial agents, pathogens, gram-positive bacteria, gram-negative bacteria

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